Bioinformatics Scientist

EOE Statement We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.

About the Organization ACI Federal is a government contractor based in Fredericksburg, Virginia. ACI has employees nationwide specializing in healthcare, information technology and national security.

ACI currently provides staff to state and Federal government agencies in classified and non-classified positions and health care staffing.

Description

ACI Federal is seeking a Bioinformatics Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the National Institute of Environmental Health Sciences (NIEHS) located in Research Triangle Prk, NC.

Overall Position Summary and Objectives

Coordinate the progress on multiple bioinformatics projects in various stages of completion while taking principal responsibility on projects as needed Collaborate with and support scientists to design experiments, analyze and interpret high throughput biological data Write relevant sections of manuscripts, prepare publication quality figures. Establish reproducible data analysis pipelines and standard operating procedures (SOPs)

Deliverables:

• Work products and documents related to applying computational data analysis approaches to make biological discoveries; identify and solve scientific or technical problems; analyze and interpret high throughput biological data; prepare and present the results to scientific peers at internal meetings as well as scientific meetings

• Work products and documents related to developing analytical approaches to integrate data generated internally; write data analysis and discussion sections of manuscripts, prepare publication quality figures; assist with additional sections of manuscripts as needed; deposit data to external or DTT-designated repositories.

• Work on products and documents related to developing and maintaining custom software and pipelines; evaluate and utilize commercial and open-source software; support the design and development efforts; establish reproducible data analysis pipelines and SOPs; provide detailed documentation for methodologies. - Weekly

• Meet with lab members to present updates - Weekly

Work Details:

• Research and review literature to retrieve targeted clinical or scientific information, including novel statistical methods, from publicly available resources. 1

• Collaborate with staff to review current and historical procedures for the acquisition, quality control, and management of data. 2

• Analyze and evaluate data cleaning and harmonization needs in the using a variety of descriptive statistics and analytic methods. 3

• Collaborate with experimentalists and computational biologists to develop new computational tools to answer research questions of interest. 4

• Identify new tools and resources for reaching biologically meaningful conclusions. 5

• Provides programming and troubleshooting support to the federal government in the dissemination of research data.

• Generate and optimize programs and scripts for the analysis of data; create programs and algorithms; and develop computational infrastructure resources for organizing and parsing data from large and complex data.

• Serve as bioinformatics expert and coordinate with teams of biologists to conduct experimental queries and/or perform portions of studies using complex procedures and techniques common to modern bioinformatics

• Coordinate building bioinformatics infrastructure to ensure easy and meaningful scientific analysis and interpretation of data.

• Provide broad-based programming and analytic support for a wide variety of bioinformatic and research projects

• Install, troubleshoot, and run open-source and commercial scientific software on platforms.

• Performs computations on research data analysis.

• Perform computational analysis of, and interpret results.

• Provide reports based on analysis of scientific data.

• Perform sequencing and alignment of raw data, and interpret new data using larger public access datasets.

• Provide interpretive analyses of data derived from different experimental platforms to generate biological meaning.

• Write custom programs and algorithms to support data analyses and discovery.

• Works with staff on scientific programming and experimental design.

• Collaborate with scientists to design, analyze, manage, and interpret all types of data.

• Design and execute computational experiments.

• Work with staff on planning of experiments, and data analysis for internal and collaborative projects; usebioinformatics expertise to advise and help bench scientists on experimental design and troubleshooting.

• Work with staff to develop specifications for new analysis; design, test and implement solutions.

• Make recommendations to investigators about the correct computational tools for testing scientific hypotheses andreaching valid conclusions.

• Records observations and reports results at weekly laboratory meetings.

• Maintain proper and detailed documentation of the analysis performed and report results at lab meetings.

• Attend scientific and programming meetings; take and compile comprehensive notes; and organize and edit content of meeting reports.

• Prepare scientific reports and progress reports; assemble data to prepare tables, graphs, and slides; conduct scientific and program-related information searches and report results.

• Organize daily laboratory notebook on experiments; prepare weekly updates on ongoing experiments and tasks;provide monthly progress notes on assigned projects; submit final progress reports and future directions on projects.

• Organize laboratory notebook or computer database to record results of calculations. Share results at lab meetings.

• Provides statistical support/analysis of research data.

• Devise novel methods of statistical analysis for the collected data.

• Utilize and adapt existing bioinformatics techniques to check for trends and patterns in the data.

• Write complex queries to multiple databases.

• Perform data processing and data analysis with existing computational and statistical methods.

• Assist in evaluating and interpreting results for validity and scientific meaning.

• Provides research/service goals in the context of the laboratory's overall mission.

• Create novel programs and algorithms that facilitate discovery of knowledge in investigating large and complex data.

• Develop and optimize programs and scripts that facilitate the organization, integration, and data-mining of large data sets; integrate these models into a framework of best practices.

• Participate in the design of new protocols involving computational methods.

• Work with staff on the development and maintenance of bioinformatics tools, scripts, and pipelines for data.

• Participate in research design with investigators to determine best practices pertaining to the bioinformaticsanalysis in new and ongoing projects.

• Evaluates new types of experimental approaches to protocols based on knowledge of scientific literature, availablefacilities and research needs.

• Independently coordinates the training of personnel in the use of scientific software applications, statisticalsoftware applications and programmatic software applications.

• Provide training in and technical support (including product updates and version control) for programs, algorithms,archives, and pipelines generated during the course of this work.

• Instruct staff in computational analysis of data.

• Provide ad hoc trainings and hands-on workshops on the use of bioinformatics tools.

• Provide training of students, new investigators, and other laboratory personnel in the use of techniques, proceduresand equipment to complete the objectives of the laboratory.

• Onboard and train staff involved in new clinical trials, including the import of a wide variety of legacy data set; provide rigorous quality control of these data.

1, 2, 3, 4, 5 represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked

Minimum Education

Masters

Additional Qualifications:

Certifications & Licenses:

• Amazon Web Services (AWS) Certification

Field of Study:

• Genetics

• Molecular Biology

• Computer Programming and Data Processing

• Statistics and Decision Science

Software:

• SQL

• R

• PERL

• Python

• Linux

Skills:

• Next-Gen Sequencing Data Analysis: Bulk RNA-Sequencing

• Clinical and/or Translational Research

• Work with Large Data Sets

• Microarray Data Analysis

• Whole Genome Sequencing

Apply now!

Full-Time/Part-Time Full-Time

Position Bioinformatics Scientist

Position Requirements

User4

Self-ID for Veteran Status

Self-ID of Disability

This position is currently accepting applications.